The Los Angeles Lakers had the highest point differential by a team in a 2023 playoff game, with a 40 point differential versus the Grizzlies on April 28, 2023.

nba largest margin of victory in playoffs by game 2023

TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	TOV	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	PF
Los Angeles Lakers	40	4/28/2023	LAL	vs	MEM	W 125-85	240	125	52	33	6	15	13	49	91	53.8	15	44	34.1	12	15	80.0	16
Boston Celtics	34	5/3/2023	BOS	vs	PHI	W 121-87	240	121	46	26	6	8	6	43	92	46.7	20	51	39.2	15	16	93.8	17
Los Angeles Lakers	30	5/6/2023	LAL	vs	GSW	W 127-97	240	127	44	27	10	6	12	42	80	52.5	15	31	48.4	28	37	75.7	21
Denver Nuggets	29	4/16/2023	DEN	vs	MIN	W 109-80	240	109	54	24	6	4	10	41	90	45.6	16	39	41.0	11	17	64.7	20
Golden State Warriors	27	5/4/2023	GSW	vs	LAL	W 127-100	240	127	55	38	2	3	15	48	95	50.5	21	42	50.0	10	16	62.5	23
Miami Heat	26	5/21/2023	MIA	vs	BOS	W 128-102	240	128	35	25	7	4	9	46	81	56.8	19	35	54.3	17	21	81.0	16
Denver Nuggets	25	5/11/2023	DEN	@	PHX	W 125-100	240	125	41	24	10	3	10	44	82	53.7	8	22	36.4	29	31	93.5	22
Boston Celtics	24	5/14/2023	BOS	vs	PHI	W 112-88	240	112	43	18	7	7	7	41	87	47.1	15	33	45.5	15	18	83.3	13
Miami Heat	22	4/22/2023	MIA	vs	MIL	W 121-99	240	121	44	22	13	4	13	45	84	53.6	16	33	48.5	15	17	88.2	18
Los Angeles Lakers	21	5/12/2023	LAL	vs	GSW	W 122-101	240	122	46	25	6	6	6	39	75	52.0	13	26	50.0	31	42	73.8	17
Golden State Warriors	20	4/30/2023	GSW	@	SAC	W 120-100	240	120	55	25	4	6	7	43	100	43.0	15	46	32.6	19	30	63.3	23
New York Knicks	20	4/21/2023	NYK	vs	CLE	W 99-79	240	99	45	21	14	5	14	39	83	47.0	10	33	30.3	11	18	61.1	17
Philadelphia 76ers	20	4/15/2023	PHI	vs	BKN	W 121-101	240	121	38	32	14	3	8	42	89	47.2	21	43	48.8	16	16	100.0	17
Miami Heat	19	5/29/2023	MIA	@	BOS	W 103-84	240	103	42	26	7	2	12	42	86	48.8	14	28	50.0	5	6	83.3	15
Miami Heat	19	5/6/2023	MIA	vs	NYK	W 105-86	240	105	50	17	3	5	13	35	90	38.9	7	32	21.9	28	31	90.3	25
Sacramento Kings	19	4/28/2023	SAC	@	GSW	W 118-99	240	118	53	25	10	8	19	40	99	40.4	17	45	37.8	21	25	84.0	26
Denver Nuggets	18	4/29/2023	DEN	vs	PHX	W 125-107	240	125	49	22	14	1	9	48	101	47.5	16	37	43.2	13	15	86.7	19
Boston Celtics	17	5/23/2023	BOS	@	MIA	W 116-99	240	116	39	28	8	8	10	43	84	51.2	18	45	40.0	12	18	66.7	24
Memphis Grizzlies	17	4/26/2023	MEM	vs	LAL	W 116-99	240	116	52	24	6	2	11	44	99	44.4	14	40	35.0	14	17	82.4	19
Golden State Warriors	17	4/20/2023	GSW	vs	SAC	W 114-97	240	114	59	31	12	5	11	40	100	40.0	16	50	32.0	18	23	78.3	19
Cleveland Cavaliers	17	4/18/2023	CLE	vs	NYK	W 107-90	240	107	43	26	10	7	17	38	77	49.4	14	33	42.4	17	21	81.0	22
Denver Nuggets	16	5/9/2023	DEN	vs	PHX	W 118-102	240	118	50	32	6	6	10	42	85	49.4	13	27	48.1	21	28	75.0	17
Milwaukee Bucks	16	4/19/2023	MIL	vs	MIA	W 138-122	240	138	45	35	9	4	11	53	99	53.5	25	49	51.0	7	8	87.5	16
Los Angeles Lakers	16	4/16/2023	LAL	@	MEM	W 128-112	240	128	45	25	7	11	14	49	92	53.3	16	37	43.2	14	16	87.5	18
Denver Nuggets	15	6/7/2023	DEN	@	MIA	W 109-94	240	109	58	28	3	5	13	41	80	51.3	5	18	27.8	22	27	81.5	18