The Chicago Bulls have the highest point differential by a team in a game 6, with a 54 point differential in Game 6 of the 2015 First Round against the Bucks.

highest point different combined in game 6 and game 7

TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	TOV	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	PF
Chicago Bulls	54	4/30/2015	CHI	@	MIL	W 120-66	240	120	50	31	7	2	12	46	90	51.1	15	30	50.0	13	16	81.3	14
Minnesota Timberwolves	45	5/16/2024	MIN	vs	DEN	W 115-70	240	115	62	26	9	4	6	40	86	46.5	15	40	37.5	20	24	83.3	14
Los Angeles Lakers	40	4/28/2023	LAL	vs	MEM	W 125-85	240	125	52	33	6	15	13	49	91	53.8	15	44	34.1	12	15	80.0	16
Los Angeles Lakers	40	4/5/1969	LAL	@	SFW	W 118-78	240	118	69	28				48	98	49.0				22	30	73.3	18
San Antonio Spurs	39	5/11/2017	SAS	@	HOU	W 114-75	240	114	60	32	8	9	7	51	96	53.1	5	22	22.7	7	13	53.8	21
Boston Celtics	39	6/17/2008	BOS	vs	LAL	W 131-92	240	131	48	33	18	4	7	43	87	49.4	13	26	50.0	32	37	86.5	25
Philadelphia 76ers	35	4/28/2022	PHI	@	TOR	W 132-97	240	132	47	32	4	4	11	47	81	58.0	16	40	40.0	22	23	95.7	22
Utah Jazz	35	5/30/1996	UTA	vs	SEA	W 118-83	240	118	37	35	15	7	11	44	73	60.3	6	15	40.0	24	30	80.0	25
Washington Bullets	35	6/4/1978	WAS	vs	SEA	W 117-82	240	117	69	26	12	10	21	46	103	44.7				25	34	73.5	25
Indiana Pacers	34	4/27/2018	IND	vs	CLE	W 121-87	240	121	45	27	9	1	7	49	87	56.3	15	30	50.0	8	14	57.1	18
Boston Celtics	31	5/15/1992	BOS	vs	CLE	W 122-91	240	122	44	41	11	6	9	52	88	59.1	0	6	0.0	18	22	81.8	17
Golden State Warriors	29	5/26/2018	GSW	vs	HOU	W 115-86	240	115	47	26	11	10	12	43	87	49.4	16	38	42.1	13	19	68.4	17
San Antonio Spurs	28	5/15/2003	SAS	@	LAL	W 110-82	240	110	44	21	9	4	10	44	79	55.7	6	9	66.7	16	23	69.6	19
Utah Jazz	28	5/19/1988	UTA	vs	LAL	W 108-80	240	108	41	27	11	4	10	38	80	47.5	3	4	75.0	29	36	80.6	22
Milwaukee Bucks	28	4/30/1978	MIL	vs	DEN	W 119-91	240	119	63	35	10	10	17	53	114	46.5				13	18	72.2	18
St. Louis Hawks	28	4/12/1964	STL	vs	SFW	W 123-95	240	123	54	30				49	99	49.5				25	33	75.8	28
Dallas Mavericks	27	5/12/2022	DAL	vs	PHX	W 113-86	240	113	39	18	16	4	6	35	77	45.5	16	39	41.0	27	36	75.0	23
Phoenix Suns	27	6/30/2021	PHX	@	LAC	W 130-103	240	130	47	27	5	4	9	53	94	56.4	17	31	54.8	7	11	63.6	21
Los Angeles Lakers	27	5/29/2009	LAL	@	DEN	W 119-92	240	119	38	28	6	4	13	43	75	57.3	9	16	56.3	24	24	100.0	19
Utah Jazz	27	5/16/1996	UTA	vs	SAS	W 108-81	240	108	47	29	3	7	10	41	79	51.9	7	13	53.8	19	25	76.0	26
Indiana Pacers	27	6/2/1995	IND	vs	ORL	W 123-96	240	123	54	34	7	2	12	47	84	56.0	9	18	50.0	20	27	74.1	24
Cleveland Cavaliers	26	5/27/2016	CLE	@	TOR	W 113-87	240	113	38	22	6	6	10	40	74	54.1	17	31	54.8	16	21	76.2	18
Miami Heat	26	5/1/2009	MIA	vs	ATL	W 98-72	240	98	47	12	5	5	11	35	74	47.3	7	21	33.3	21	24	87.5	21
Denver Nuggets	25	5/11/2023	DEN	@	PHX	W 125-100	240	125	41	24	10	3	10	44	82	53.7	8	22	36.4	29	31	93.5	22
Miami Heat	25	5/30/2014	MIA	vs	IND	W 117-92	240	117	37	24	7	4	9	44	76	57.9	11	26	42.3	18	21	85.7	22