Brook Lopez has put up his most career points per game versus the Trail Blazers, with 19.3 per game.

brook lopez highest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Trail Blazers	19.3	26	30.6	5.8	1.5	0.9	1.2	1.3	7.7	13.5	56.5	1.1	2.9	38.7	2.8	3.5	81.3	796	501	150	40	24	32	33	73	+93
Lakers	19.1	24	33.9	8.0	1.8	0.6	1.9	1.8	7.1	14.2	50.0	1.0	2.7	39.1	3.9	5.2	75.8	814	459	191	43	14	46	43	70	-25
Raptors	17.8	42	30.9	6.5	1.5	0.6	2.1	1.8	6.8	13.9	49.1	0.7	2.2	30.1	3.5	4.1	83.3	1,299	747	273	61	24	88	74	116	-77
Thunder	17.5	26	29.7	6.1	1.0	0.8	1.6	1.6	6.8	13.8	49.0	1.2	3.1	38.3	2.8	3.3	83.9	773	456	159	27	20	42	42	63	+37
Mavericks	17.4	28	30.3	6.5	1.4	0.6	1.3	1.2	6.7	13.5	49.5	1.1	2.8	39.0	3.0	3.8	77.6	848	487	183	39	17	37	33	71	+47
Knicks	17.1	47	30.9	6.7	1.6	0.7	2.7	1.7	6.6	13.4	49.4	0.9	2.7	33.9	2.9	3.7	79.7	1,454	804	314	77	34	125	79	115	+54
Bulls	17.1	46	31.2	5.9	1.2	0.5	1.9	1.3	6.5	13.2	49.7	1.0	3.0	32.4	3.0	3.7	81.4	1,435	786	271	54	23	86	58	125	+108
Bucks	17.1	28	31.7	6.3	1.7	0.4	2.0	1.9	6.4	12.4	51.7	0.5	1.2	42.4	3.7	5.0	74.3	887	478	175	48	12	57	53	69	-174
Pistons	17.0	43	30.2	6.8	1.8	0.4	2.3	1.4	6.5	11.6	55.8	1.2	2.9	40.0	2.9	3.6	81.7	1,298	733	293	78	17	98	61	114	+269
Hornets	16.7	41	30.0	6.2	2.0	0.5	2.0	1.9	6.3	12.5	50.6	0.8	2.4	33.7	3.2	3.8	84.7	1,231	684	255	80	22	84	78	116	+204
Wizards	16.6	43	29.9	6.3	1.7	0.6	2.0	1.7	6.3	11.8	53.1	0.8	2.1	38.2	3.3	4.1	80.7	1,286	714	271	74	24	87	75	121	+56
Hawks	16.3	45	30.2	5.8	1.4	0.5	1.6	1.8	6.2	12.0	51.2	1.1	2.6	40.3	3.0	3.7	80.1	1,358	735	262	64	24	72	79	102	-81
Pacers	16.2	45	30.3	6.0	1.3	0.6	2.0	1.7	6.1	12.8	47.8	0.8	2.6	32.2	3.1	4.0	77.7	1,362	729	272	60	29	88	75	121	+20
Rockets	16.1	26	29.8	6.5	1.2	0.5	2.5	1.8	6.1	11.9	51.5	0.6	2.0	31.4	3.3	3.9	83.3	774	419	170	31	14	64	47	62	-30
Suns	16.1	28	31.2	7.2	1.1	0.6	1.7	1.9	6.3	13.1	47.8	0.8	3.1	26.4	2.8	3.6	77.2	873	451	202	30	16	48	53	72	+49
76ers	16.0	47	30.6	6.2	1.6	0.4	1.7	1.8	6.0	12.3	48.9	1.2	3.0	39.3	2.8	3.5	81.6	1,439	754	292	73	19	80	85	133	+302
Pelicans	16.0	26	30.2	6.0	1.7	0.7	1.7	1.5	6.2	12.0	51.8	1.0	2.8	34.7	2.7	3.5	75.0	786	416	156	43	19	45	39	68	+85
Cavaliers	15.7	42	31.8	7.1	1.6	0.6	1.8	1.5	5.9	12.2	48.6	0.8	2.3	36.5	3.0	3.8	78.6	1,334	658	299	66	25	74	65	115	+93
Clippers	15.5	27	31.3	6.2	1.6	0.6	2.0	1.3	6.1	11.9	51.9	0.9	2.5	37.3	2.3	2.9	77.2	845	418	167	42	15	53	34	70	+66
Celtics	15.5	48	30.0	5.6	1.2	0.4	1.6	1.8	5.8	11.7	49.8	0.6	2.1	31.0	3.2	3.9	82.8	1,440	743	268	57	20	77	87	102	-35
Nuggets	15.5	28	28.6	5.1	1.6	0.3	1.2	1.6	5.8	12.1	47.9	1.2	3.1	39.5	2.6	3.3	79.3	800	433	142	46	8	33	44	87	+33
Kings	15.2	30	29.2	6.3	1.3	0.3	2.2	1.5	5.7	12.3	46.2	1.0	3.0	33.3	2.8	3.4	83.3	877	457	189	40	8	65	44	98	+118
Timberwolves	15.2	26	29.4	6.7	1.4	0.7	2.0	1.9	6.0	11.2	53.6	1.1	3.0	37.7	2.1	3.0	68.4	765	395	173	36	19	53	49	74	+49
Heat	15.0	43	29.9	5.9	1.1	0.4	1.4	1.5	5.7	12.2	46.8	0.9	2.5	34.9	2.8	3.5	78.8	1,285	647	252	49	19	61	65	104	-8
Warriors	15.0	25	29.6	5.8	1.6	0.9	1.7	1.9	6.0	12.2	48.9	0.6	2.5	24.2	2.4	3.0	81.3	739	374	144	40	23	43	47	61	-74